Denik Pharma Fertireline | GnRH Decapeptide

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  • Composition : GnRH Decapeptide
  • Potency : 200mcg /vial
  • Quantity : GnRH Decapeptide x 1 vial ,  2ml Sterile water for injection.
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Description

Denik Pharma Fertireline | GnRH Decapeptide

GNRH Decapeptide (Gonadotropin-Releasing Hormone Analogue)
Vial: 200 mcg
Ampoule: 2 mL Sterile Water for Injection
Form: Lyophilised (freeze-dried) powder
Route: Subcutaneous (SC) or Intramuscular (IM) injection after reconstitution
Product Overview
Fertirelin by Denik Pharma is a synthetic Gonadotropin-Releasing Hormone (GnRH) analogue, designed to mimic the activity of natural GnRH — a key hormone that regulates reproductive hormone release from the pituitary gland. As a GnRH decapeptide, Fertirelin stimulates the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are essential for reproductive function.
⚠️ Fertirelin and other GnRH analogues are typically studied in research or veterinary contexts and may not be approved for human therapeutic use unless prescribed and monitored by qualified healthcare professionals.
How FERTIRELIN Works
Fertirelin binds to GnRH receptors in the pituitary gland, triggering the release of key reproductive hormones:
•LH (Luteinizing Hormone) — supports ovulation in females and testosterone production in males
•FSH (Follicle-Stimulating Hormone) — supports follicle development in females and spermatogenesis in males
By mimicking the natural GnRH signal, Fertirelin can help regulate hypothalamic-pituitary-gonadal (HPG) axis activity for reproductive hormone modulation.
Potential Benefits
✔ Stimulates Reproductive Hormone Release
Fertirelin can stimulate the secretion of LH and FSH, supporting reproductive hormone signaling pathways that are key to fertility research and pituitary function studies.
✔ Research Use in Endocrine Pathways
Due to its potent GnRH analogue action, Fertirelin is valuable in researching hormonal control, pituitary function, and reproductive endocrinology.
✔ May Support Fertility-Related Investigations
Because LH and FSH are required for ovarian follicle development and spermatogenesis, Fertirelin serves as a tool in preclinical or veterinary reproductive research.
✔ Potent GnRH Agonist Activity
Fertirelin is a potent structural analogue that mimics natural hormone signaling, which can help researchers explore pituitary-mediated hormone release mechanisms.
Note: The benefits listed are based on the biological role of GnRH agonists in hormonal regulation and controlled research data. Outcomes depend on rigorous study design and professional oversight.
Common Side Effects
GnRH analogues such as Fertirelin can exert significant effects on reproductive hormone balance. In human and clinical contexts with similar peptides, reported side effects include:
(Adapted from clinical data on GnRH agonists.)
•Headache
•Nausea
•Injection-site reactions (pain, redness, swelling)
•Hot flushes or sweating
•Mood changes or irritability
•Dizziness or light-headedness
These effects are generally related to hormonal fluctuations triggered by GnRH receptor activation.
Less Common / Potential Side Effects
Long-term or repeated stimulation of the GnRH axis in clinical use may cause hormonal suppression effects or secondary reactions. Reported effects with GnRH agonists include:
•Weight fluctuations
•Muscle or joint pain
•Changes in libido
•Vaginal dryness or menstrual changes (in females)
•Bone metabolism effects with prolonged use (e.g., reduced bone density)
•Allergic reactions (rare)
Because Fertirelin is an active endocrine modulator, use in humans should only be conducted under strict medical supervision.
Important Safety Information
•Professional Guidance Required: Fertirelin should only be administered under qualified supervision, such as in research settings or when prescribed by an endocrinologist or reproductive specialist.
•Not a Self-Administered Product: Incorrect dosing or prolonged unsupervised use of GnRH-like peptides can lead to hormonal imbalances and significant systemic effects.
•Contraindications: Avoid use in pregnancy, breastfeeding, or in individuals with known hormone-sensitive cancers unless medically justified and monitored.
•Monitoring Recommended: In therapeutic or investigational settings, periodic hormonal profiling and clinical monitoring are important to assess response and safety.
Storage Instructions
•Before Reconstitution: Store refrigerated at 2–8 °C
•After Reconstitution: Keep refrigerated and use according to the protocol or professional guidance
•Do Not Freeze after reconstitution
Summary
Denik Pharma — FERTIRELIN (GnRH Decapeptide 200 mcg) is a synthetic growth hormone releasing peptide analogue that mimics natural GnRH to stimulate release of key reproductive hormones such as LH and FSH. It is primarily used in research settings or under professional supervision to explore endocrine regulation and reproductive hormone dynamics. While it may support hormone release pathways and scientific studies, potential side effects — including headache, nausea, mood changes, and hormonal fluctuations — underscore the importance of careful use and clinical oversight.
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Denik Pharma

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